Functional and Molecular Studies of an Interaction Between the Antigen-Presenting Molecule Mr1 and Lilr Immune Regulatory Receptors

Grant number: 1165467 | Funding period: 2019 - 2021

Completed

Abstract

Our body’s defense against invading pathogens relies on our immune system. The immune system is made up of multiple cell types that each performs different tasks. In order to function correctly, a family of molecules called inhibitory receptors regulates the immune response. This project will characterize a novel inhibitory receptor axis that we have recently discovered in humans. This may open up new avenues of cancer therapy and autoimmune therapy in the future.

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University of Melbourne Researchers

Adam Uldrich